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Parkinson's disease is a neurodegenerative movement disorder resulting in rigidity, bradykinesia (slowness), tremor and gait disorder. Deep brain stimulation (DBS) of the subthalamic nucleus has been shown to be effective in managing symptoms, but quantitative methods to facilitate the adjustment of the stimulator settings are needed. In this paper, we present preliminary results from a study aimed...
Deep brain stimulation of the subthalamic nucleus (STN DBS) is a surgical procedure used to treat the debilitating symptoms of advanced Parkinson's disease (PD); characterized by tremor, slowness of movement (bradykinesia) and involuntary movement (dyskinesia). The selection of optimal stimulation parameters is based upon subjective and qualitative clinical observations made across several programming...
Our study suggests that a sensor-based technique might be an important adjunct to existing clinical measures to improve the management of patients undergoing Parkinson's control therapy via deep-brain stimulation. In the future, clinicians could gather accelerometer data for approximately one week before and after outpatient visits for deep-brain stimulation adjustments. An expert system could then...
The objective of this pilot work is to identify characteristics and measure severity of motor fluctuations in patients with Parkinson's disease (PD) based on wearable sensor data. Improved methods of assessing longitudinal changes in PD would enable optimization of treatment and maximization of patient function. We hypothesize that motor fluctuations accompanying late-stage PD present with predictable...
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