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Background
The basal cell adhesion molecule (BCAM) carries the antigens of the Lutheran (LU, ISBT005) system. We report a novel Lutheran antigen and propose an updated, full‐length 3D model of BCAM.
Study Design and Methods
Red blood cell testing, antibody identification, and BCAM genomic DNA sequencing were done by standard methods. Multi‐template homology modeling of BCAM used structural templates...
Background
Scianna (Sc) antigens, seven high and two of low prevalence, are expressed on erythrocyte membrane‐associated protein (ERMAP). We investigated SC (ERMAP) in individuals who made antibodies to high prevalence Scianna antigens, and propose a 3D model for ERMAP to precisely localize the residues associated with the known antigens.
Methods
Serological testing and DNA sequencing was performed...
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