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RH genotyping is particularly useful in clinical transfusion practice to discriminate partial D from weak D, distinguish alloantibodies from autoantibodies, detect the absence of high-prevalence Rh antigens, and to screen for Rh-compatible donors. Because of the complexity of the RH locus, many areas of RHD and RHCE must be sampled for accurate genotyping; gene sequencing is often required. Manual...
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