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Vibrio vulnificus is an aquatic pathogen that can cause primary sepsis and soft tissue infection. CpG oligodeoxynucleotides (CpG‐ODN) are a type of essential immunomodulators, which can trigger or enhance immune responses in mammals, fish and humans. In this study, we evaluated the effect of CpG‐ODN 2007 as a potential immunostimulant for zebrafish (Danio rerio) infected with V. vulnificus strain...
Adjuvants have been proven to be very effective in enhancement of immune response of many antigens. However, few studies involved head-to-head comparison of their potentials in inactive rabies virus vaccine. In this study, we investigated two types of aluminum adjuvants and five other adjuvants (BLPs, AS02, AS03, MF59 and Poly I:C) on their capacity in enhancing the efficacy of rabies vaccine. The...
Shell matrix proteins play an important role in the regulation of shell growth and formation in the pearl oyster, Pinctada fucata. This study compared the expression levels of seven shell matrix protein genes (aspein, prismalin-14, n16, n19, nacrein, msi7, and efcbp) in pearl oysters of various sizes [large (L), medium (M), and small (S)] and analyzed the correlations between expression level and...
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