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Background
This study aims to investigate the characteristic role of inhibitory receptor leukocyte‐associated immunoglobulin‐like receptor 1 (LAIR‐1) in oral squamous cell carcinoma (OSCC).
Methods
The expressions of LAIR‐1 and other immune‐related molecules were detected in a human OSCC tissue microarray. LAIR‐1 expression difference among different clinicopathological parameters was analyzed...
Checkpoint blockade therapy utilizing monoclonal antibodies to reactivate T cells and recover their antitumor activity makes an epoch in cancer immunotherapy. The role of B7-H4, a novel negative immune checkpoint, in oral squamous cell carcinoma (OSCC) has still not been elucidated. In this study, tissue samples from human OSCC, which contains 165 primary OSCC, 48 oral epithelial dysplasia and 43...
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