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During mRNA translation, the ribosomal density profile along the coding region of the mRNA molecule affects various fundamental intracellular phenomena. Thus, steering this profile from a given to a desired density is an important biological problem. This paper studies this problem using a dynamical model for mRNA translation, called the ribosome flow model (RFM), in which one views the transition...
Output-saturated systems are linear systems whose outputs are saturated away from zero. We present conditions for observability of this class of systems.
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