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Objective To study the mechanism of IFN on CML. Methods Samples of 15 CML patients and 10 healthy controls were studied. The flow cytometry was performed to identify circulating pDCs. The concentration of IFN-α in serum and that in the supernatant of peripheral blood mononuclear cells (PBMCs) cultured after stimulation with CpG ODN2216 were examined both in CML patients and in the healthy controls...
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