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A red alga, Chondria armata, was used as a vermifuge in Japan. Previously, we isolated domoic acids from C. armata guided by the insecticidal activity against American cockroaches. Further investigations led to the discovery of a compound one-thousand times more toxic than domoic acid. It showed lethal activity at 5ng against cockroaches. The insecticidal compound was identified as palytoxin by means...
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