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Tumor necrosis factor-α (TNF-α) is found to play important roles in acute myocardial infarction (AMI). Ventricular arrhythmias arising from AMI are leading causes of sudden cardiac death (SCD). We sought to clarify the effect of TNF-α early expression on ventricular arrhythmias in rats with AMI and its mechanism.Rats with AMI were induced by left anterior descending coronary branch ligation. The mRNA...
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