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Background The incomplete ground truth of training data of B-cell epitopes is a demanding issue in computational epitope prediction. The challenge is that only a small fraction of the surface residues of an antigen are confirmed as antigenic residues (positive training data); the remaining residues are unlabeled. As some of these uncertain residues can possibly be grouped to form novel but currently...
In this paper, we present a new optimization based motion planning method for dynamic environments. Compared with the optimization method proposed by Esposito and Kumar (2002), our optimization method based on modified Newton's method can greatly improve the performance with very modest computation effort. To illustrate our techniques, we consider a robot team motion planning problem in a complex...
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