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A 16-kDa protein toxin was purified fromHirsutella thompsoniivarthompsoniiand named hirsutellin A (HtA). At 0.5 and 5.0 μmconcentrations, HtA caused detectable cytopathic effects onSpodoptera frugiperdacells (Sf-9) within 2–4 hr and completely inhibited Sf-9 cell growth at 4 days posttreatment. Electron microscope data showed that the HtA treated Sf-9 cells became hypotrophied and internal organelles...
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