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Study Objective
To develop and validate a model for predicting acute kidney injury (AKI) after high‐dose methotrexate (HDMTX) exposure.
Design
Retrospective analysis.
Setting
Multisite integrated health system throughout Minnesota and Wisconsin.
Patients
Adult patients with lymphoma who received HDMTX as a 4‐h infusion.
Measurements and Main Results
LASSO methodology was used to identify...
Over the last decade, the discovery of novel renal biomarkers and research on their use to improve medication effectiveness and safety has expanded considerably. Pharmacists are uniquely positioned to leverage this new technology for renal assessment to improve medication dosing and monitoring. Serum cystatin C is a relatively new, inexpensive, functional renal biomarker that responds more quickly...
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