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Metabolic syndrome is known as a frequent precursor of type 2 diabetes mellitus (T2D). This disease could affect 8% of the people worldwide. Given that pancreatic β‐cell dysfunction and loss have central roles in the initiation and progression of the disease, the understanding of cellular and molecular pathways associated with pancreatic β‐cell dysfunction can provide more information about the underlying...
BackgroundObesity is linked to insulin resistance (IR), which can lead to type 2 diabetes mellitus. Oxidative stress present in early obesity may favor the progression to comorbid conditions.
ObjectiveTo examine the relationship between oxidative stress biomarkers and the severity of IR in a group of obese children.
MethodsForty obese children with a body mass index (BMI) Z‐score ≥ 2 were divided...
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