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Phosphoinositides are minor constituents of eukaryotic membranes but participate in a wide range of cellular processes. The most abundant and best characterized phosphoinositide species are phosphatidylinositol 4,5-bisphosphate (PI(4,5)P 2 ) and its main precursor, phosphatidylinositol 4-phosphate (PI4P). PI4P and PI(4,5)P 2 regulate various structural and developmental functions but...
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