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Detergent‐mediated virus inactivation (VI) provides a valuable orthogonal strategy for viral clearance in mammalian processes, in particular for next‐generation continuous manufacturing. Furthermore, there exists an industry‐wide need to replace the conventionally employed detergent Triton X‐100 with eco‐friendly alternatives. However, given Triton X‐100 has been the gold standard for VI due its minimal...