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Objective
Oral squamous cell carcinoma (OSCC) represents 3%–4% of all cancers. Despite the increasing incidence of OSCC distant metastasis and poor prognosis, few animal models of OSCC distant metastasis have been reported. In this study, we established mouse models of OSCC lung metastasis by orthotopic and tail vein injection of new OSCC cell lines.
Methods
For the tail vein model, we used a novel...
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