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Aims
The current study aimed to explore the expression of transient receptor potential A1 ion channels (TRPA1) in the rat ureter and to assess if TRPA1‐active compounds modulate ureter function.
Methods
The expression of TRPA1 in rat ureter tissue was studied by immunofluorescence. The TRPA1 distribution was compared to calcitonin gene‐related peptide (CGRP), α‐actin (SMA1), anoctamin‐1 (ANO1),...
Aims
Mechanoafferent and peristaltic mechanisms of the human ureter involve transient receptor potential V1 (TRPV1)‐ and purinoceptor‐mediated functions. Hydrogen sulphide, an endogenous TRPA1 ligand, is linked to inhibitory neurotransmission of the pig ureter. No information is available on TRPA1 activity in the human ureter. We therefore examined the distribution and function of TRPA1 in the human...
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