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This paper reports a novel microfluidic worm immobilization device that enables, for the first time, automated, high-speed microinjection of the nematode worm Caenorhabditis elegans. The microfluidic device, integrated with an automated robotic system, is capable of sequentially loading, immobilizing, injecting, and sorting C. elegans with minimal human intervention. Using the device, we demonstrate...
This paper reports, for the first time, an electrochemical microfluidic paper-based analytical device (EμPAD), featuring a highly-sensitive working electrode (WE) decorated with zinc oxide nanowires (ZnO NWs), for glucose detection in human serum. Besides common features of μPADs such as low cost, high portability/disposability, and ease of operation, the reported EμPAD has three additional advantages...
The nematode worm Caenorhabditis elegans has been employed as a popular model organism in many fields of biological research. In this paper, we present a microfluidic device for facilitating chemical testing using C. elegans . For testing chemicals on chip, the device houses single nematodes in microfluidic chambers and precisely adjusts the chamber’s chemical environment...
Paper-based microfluidic devices have emerged as simple yet powerful platforms for performing low-cost analytical tests. This paper reports a microfluidic paper-based electrochemical biosensor array for multiplexed detection of disease markers. Different from existing paper-based electrochemical biosensors, our device includes an array of eight electrochemical sensors and utilizes a custom-made, handheld...
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