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APELA is a small, secreted peptide that can function as a ligand for the G-protein coupled receptor, Apelin Receptor (APLNR, APJ). APELA plays an essential role in endoderm differentiation and cardiac development during embryogenesis. We investigated whether APELA exerts any functions in cancer progression.The Cancer Genome Atlas (TCGA) RNA sequencing datasets, microarray from an OCCC mouse model,...
Objective. The aim of this study is to investigate the prevalence of promotor CpG island methylation of the death-associated protein kinase (DAPK), p16, and O 6 -methylguanine-DNA methyltransferase (MGMT) genes in both tumor and plasma samples of cervical cancers.Methods. Methylation-specific PCR (MSP) was employed to detect promotor CpG island methylation of the DAPK, p16, and MGMT genes...
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