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Here, we provide the NMR spectra and AFM data for antioxidant micelles prepared from amphiphilic PAM-PDA block copolymers composed of a poly(N-acryloyl morpholine) and a redox-active catechol-bearing block with different catechol content. We also provide details of the electrochemical analysis that showed micelles higher catechol content had a similar redox potential with the small catechol compound...
Oxidative stress caused by uncontrolled production of reactive oxygen species (ROS) has been linked to the initiation and progression of some diseases. Therefore, the use of antioxidants capable of scavenging ROS has attracted growing interest. We recently reported antioxidant micelles having catechol moieties, a structural motif found among natural antioxidants. These micelles showed a strong inhibitory...
Reactive oxygen species (ROS) are mainly formed by metabolism of oxygen in the human body and play essential roles in cell signaling, pathogen defense, and homeostasis. However, elevated levels of these species have been linked to inflammatory diseases such as arthritis as well as tumor growth. For this reason, the therapeutic use of antioxidants, compounds capable of inactivating these ROS...
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