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Block copolymers composed of poly(ethylene glycol) with a molecular weight of 2 K and poly(amino acid) random copolymers with 70 mol% L-lysine and 30 mol% L-phenylalanine residues were conjugated with 10, 20 and 30 mol% histidine derivatives at the primary amino end group of the L-lysines. The complex formation of the copolymer and plasmid DNA (pDNA) was confirmed by a gel retardation assay and complete...
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