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This work was performed to characterize the possible mechanisms involved in the anxiolytic-like activity of gallic acid (GA) in the rat elevated plus maze (EPM) test. Male Wistar rats were acutely treated with a single dose of GA (10–500mg/kg, i.p.) or diazepam and buspirone, 30min prior to behavioral assessment in the EPM, open-field and rotarod tests. Treatment with GA markedly produced an increase...
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