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Cancer is a disease characterized largely by the accumulation of out-of-control somatic mutations during the lifetime of a patient. Distinguishing driver mutations from passenger mutations has posed a challenge in modern cancer research. With the advanced development of microarray experiments and clinical studies, a large numbers of candidate cancer genes have been extracted and distinguishing informative...
For nonlinear polynomial system, the analytical formula of the Multi-dimensional Frequency Response Function are derived and the pole frequency set is defined. For applications in engineering, the extented transfer functions in one-frequency domain are defined.
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