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Background & Aims
The DEAD (Asp‐Glu‐Ala‐Asp)‐box helicase family member DDX3x has been proven to involve in hepatic lipid disruption during HCV infection. However, the role of DDX3x in non‐alcoholic fatty liver disease (NAFLD), in which lipid homeostasis is severely disrupted, remains unclear. Here, we aimed to illustrate the potential role of DDX3x in NAFLD.
Methods
DDX3x protein levels were...
Background & AimsMicroRNA‐218 (miR‐218) can function as a tumour suppressor and inactivate cancer‐promoting inflammation. However, role of miR‐218 on hepatocellular carcinoma (HCC) remains unclear. To determine the contribution of miR‐218 genetic predisposition and its interaction with hepatitis B virus (HBV) mutations to HCC risk.
Methodsrs11134527 located at putative promoter region of pre‐miR‐218...
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