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ObjectiveHydroxysafflor yellow A (HSYA) is one of the chemical component isolated from Chinese medicine Carthamus tinctorius L. Our preliminary study confirmed that HSYA attenuated bleomycin‐induced pulmonary fibrosis in mice. In this study, we evaluated the effect of HSYA on TGF‐β1‐induced activation of human fetal lung fibroblasts (MRC‐5) and explored the underlying mechanisms of its activity.
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