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In this study we use replicate 2D-LC–MS/MS analyses of crude membranes from B cells derived from a patient with chronic lymphocytic leukemia (CLL) to examine the protein expression profile of CLL B cells. Protein identifications made by replicate 2D-LC–MS/MS analysis of tryptic peptides from detergent solubilized B cell membrane proteins, as well as replicate LC–MS/MS analysis of single off-line strong...
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