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Skeletal muscle phosphorus‐31 31P MRS is the oldest MRS methodology to be applied to in vivo metabolic research. The technical requirements of 31P MRS in skeletal muscle depend on the research question, and to assess those questions requires understanding both the relevant muscle physiology, and how 31P MRS methods can probe it. Here we consider basic signal‐acquisition parameters related to radio...
PurposePhosphorus (31P) MR spectroscopic imaging (MRSI) is primarily applied with sensitive, surface radiofrequency (RF) coils that provide inhomogeneous excitation RF field (B1+) and rough localization due to their B1+ and sensitivity (B1−) profiles. A careful and time‐consuming pulse adjustment and an accurate knowledge of flip angle (FA) are mandatory for quantification corrections.
Materials...
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