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The Framingham Study which coined the term “risk factors” in middle-aged and older populations, provided the rationale for bridging the gap from youth to aging adults as part of the evolution of early natural history of cardiovascular (CV) diseases. This report details the time-course or trajectories of cardio-metabolic risk variables from childhood to adulthood in the Bogalusa Heart Study cohort...
Secondhand smoke (SHS) exposure increases cardiovascular disease risk. The objective of this study was to examine the association of SHS exposure in childhood and adulthood with adult arterial thickness.The study cohort consisted of 415 nonsmoking adults (301 whites and 114 blacks; ages 26.2–48.0 years) enrolled in 2004–2010. The arterial wall thickness was measured as common, bulb and internal carotid...
PURPOSE: Obesity and the attendant insulin resistance/hyperinsulinemia related to coronary artery disease (CAD) morbidity and mortality are well documented. However, information is lacking on the time-course relation of adiposity and fasting insulin from childhood to young adulthood in offspring of parents with CAD, a surrogate measure of future risk.METHODS: Longitudinal analysis was performed on...
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