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BACKGROUND
To the authors' knowledge, no studies to date have explored familial risks of nasopharyngeal carcinoma (NPC) in detail and quantified its lifetime risk in high‐incidence populations.
METHODS
The authors conducted a population‐based case‐control study of 2499 NPC cases and 2576 controls randomly selected in southern China from 2010 through 2014. Unconditional logistic regression was used...
Nasopharyngeal carcinoma (NPC) is a malignant tumor. This type of carcinoma has a low 5-year patient survival rate. Thus, there is a need for improved therapeutics. We determined that the Chk1 inhibitor Gö6976 enhanced the sensitivity of CNE1 and CNE2 cells to ionizing radiation (IR) or cisplatin by abrogating S and G 2 /M arrest and subsequently promoting apoptosis. Furthermore, Gö6976 appeared...
Objective Epstein-Barr virus (EBV) associated nasopharyngeal carcinoma (NPC) is an important squamous cell cancer endemic in southern China and Southeast Asia. pIgR (polymeric immunoglobulin receptor) gene plays central roles during immune responses and EBV inflammatory and therefore is a good candidate susceptibility gene for NPC. This study is to evaluated potential associations between pIgR gene...
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