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To enhance the ε-poly-l-lysine (ε-PL) productivity of Streptomyces sp. FEEL-1, a novel breeding strategy of atmospheric and room temperature plasma (ARTP) mutagenesis with streptomycin resistance screening was developed. After three rounds of recursive breeding, one strain designated AS3-14 was selected with a ε-PL yield of 2.91 g/L in shake-flask fermentation, which was elevated by 66.3 % compared...
ε-Poly-l-lysine (ε-PL)—a natural food preservative with wide antimicrobial activity and high food safety—is increasingly attracting widespread attention. However, the high cost of raw materials severely impairs its economy and utilization. In this study, agro-industrial by-products, i.e., fish meal coupled with corn steep liquor, were employed as alternative organic nitrogen sources for industrial...
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