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The control of dendritic cell (DC) migration into lymph nodes (LNs) is important for the development of more effective DC‐based immunotherapies. This study was undertaken to evaluate, dynamically and noninvasively, prostaglandin E2 (PGE2)‐enhanced migration of DCs using a 1.5 T clinical MR scanner. DC2.4 cells were labeled with superparamagnetic iron oxide (SPIO), a clinically approved MRI contrast...
This study was undertaken to compare the labeling efficiencies of three iron‐oxide based MRI contrast agents [Feridex, Resovist and monocrystalline iron oxide (MION)] and to evaluate their effects on the biological properties of human mesenchymal stem cells (hMSCs). The hMSCs were cultivated for 1 and 7 days after 24‐h labeling with iron oxide nanoparticles (12.5 µg Fe/mL) in the presence of poly‐L‐lysine...
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