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Intravital fluorescence imaging of vasculature morphology and dynamics in the brain and in tumors with large penetration depth and high signal‐to‐background ratio (SBR) is highly desirable for the study and theranostics of vascular‐related diseases and cancers. Herein, a highly bright fluorophore (BTPETQ) with long‐wavelength absorption and aggregation‐induced near‐infrared (NIR) emission (maximum...
Ultrabright organic dots with aggregation‐induced emission characteristics (AIE dots) are prepared and shown to exhibit a high quantum yield, a, large two‐photon absorption cross‐section, and low in vivo toxicity. Real‐time two‐photon intravital blood vascular imaging in various tissues substantiates that the AIE dots are effective probes for in vivo vasculature imaging in a deep and high‐contrast...
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