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Purpose To explore the impact of UDP-glucuronosyltransferase polymorphisms (UGT1A9-118(dT)9/10, UGT1A9 CI399T, UGT1A9 C-440T and UGT2B7 G211T) on the pharmacokinetics of mycophenolic acid (MPA) in healthy Chinese volunteers. Methods We recruited ten healthy volunteers with no polymorphisms (control group), 11 homozygotes of mutants UGT1A9 CI399T and UGT1A9-118(dT)9/10, ten heterozygotes of...
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