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Hederasaponin C (HSC), one of the main components of Pulsatilla chinensis, is considered as a potential drug for the treatment of inflammatory bowel disease. In the present research, we developed a pharmacokinetics–pharmacodynamics model to describe the concentration–effect course of drug action following the intraperitoneal injection of HSC in colitis rats. A sensitive UPLC–MS/MS method was established...
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