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[6]-Gingerol and [6]-shogaol are the major pungent components in ginger with a variety of biological activities including antioxidant activity. To explore their structure determinants for antioxidant activity, we synthesized eight compounds differentiated by their side chains which are characteristic of the C1–C2 double bond, the C4–C5 double bond or the 5-OH, and the six- or twelve-carbon unbranched...
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