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Pokemon has been showed to directly suppress p14 ARF expression and also to overexpress in multiple cancers. However, p14 ARF –MDM2–p53 pathway is usually aberrant in colorectal cancer (CRC). The aim is to confirm whether Pokemon plays a role in CRC and explore whether Pokemon works through p14 ARF –MDM2–p53 pathway in CRC. Immunohistochemistry for Pokemon,...
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