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Study of the degradation behavior of implants is of crucial importance in biomedical fields before practical applications. In this study, degradability of poly (DL-lactic-co-glycolic acid) (PDLGA)/poly (DL-lactide)-block-poly (ethylene glycol) (PDLA-b-PEG) scaffolds was evaluated both in vitro and in vivo. In vitro degradation of fibrous scaffolds showed that highly porous structure facilitated the...
Although sodium alginate (SA) could not be electrospun from its aqueous solution, SA-based electrospun nanofibers can be fabricated with the help of polyethylene oxide (PEO). In this study, the influence of PEO on the electrospinnability of SA aqueous solution was investigated and the roles of chain entanglements and conformations of the blend system were emphasized. It was found that a little amount...
Hyaluronic acid (HA) ultra-thin fibrous membranes by electrospinning technology had been fabricated successfully by our group. However, these HA fibrous membranes dissolve and decompose rapidly in water. In this study, chemical crosslinking of HA and HA based ultra-thin fibrous membranes was studied in detail. It was found that the chemically crosslinked pure HA ultra-thin fibrous membranes with 1-ethyl-3-(3-dimethylaminopropyl)...
Improving and understanding the electrospinnability of native cellulose in room temperature ionic liquids (RTIL) have been a hot issue in recent years. In this study, the electrospinning of cellulose in a highly efficient RTIL of 1-allyl-3-methylimidazolium chloride (AMIMCl) was investigated. The introduction of co-solvent dimethyl sulfoxide (DMSO), which significantly decreased the surface tension,...
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