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Five Ru(II) polypyridyl complexes [Ru(N–N)2(nfip)](ClO4)2 (N–N = dmb, 1; bpy, 2; ttbpy, 3, phen, 4, dmp, 5) were synthesized and characterized. The cytotoxic activities of the complexes against cancer SGC-7901, Eca-109, HepG2, A549, HeLa and normal LO2 cells were investigated using the MTT method. Complexes 1–4 show high cytotoxicity against SGC-7901 cells with low IC50 values of 12.4 ± 1.4, 6.7 ±...
An iridium(III) complex [Ir(ppy)2(MHPIP)]PF6 (ppy = 2-phenylpyridine, MHPIP = 2-(1-methyl-1H-pyrazol-3-yl)-1H-imidazo[4,5-f][1, 10]phenanthroline, Ir-1) was synthesized and characterized by elemental analysis, IR, 1H NMR and 13C NMR. The in vitro cytotoxic activities of the free proligand MHPIP and the complex Ir-1 against HepG2, A549, BEL-7402, SGC-7901 and normal LO2 cells were evaluated by the...
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