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Background
Genetic and environmental factors are important determinants of nasopharyngeal carcinoma (NPC). NPC is associated with Epstein‐Barr virus (EBV) infection. Studies have reported familial aggregation of NPC, but evidence has been mixed for elevated rates of cancers other than NPC.
Methods
The authors reassessed their previous evaluation of familial aggregation of cancer in 348 high‐risk...
Background
The 23‐valent pneumococcal polysaccharide vaccine (PPSV23) is indicated for adults who have a high risk of pneumonia; however, its effectiveness in patients with prostate cancer who are at a risk of pneumonia because of age and cancer treatments, including androgen‐deprivation therapy, is unknown.
Methods
Between 2000 and 2010, 38,735 patients with prostate cancer were diagnosed in Taiwan...
Background
Decision making regarding the initial treatment of women with breast cancer is complicated. In the current study, the authors examined the relationship between treatment choices and their children's ages among young women with early‐stage breast cancer.
Methods
Using the MarketScan Commercial Claims and Encounters database, the authors identified women aged 20 to 50 years who underwent...
Background
The thoracic radiotherapy (TRT) target volume for limited‐stage small‐cell lung cancer (SCLC) has been controversial for decades. In this report, the final results of a prospective randomized trial on the TRT target volume before and after induction chemotherapy are presented.
Methods
After 2 cycles of etoposide and cisplatin, patients arm were randomized to receive TRT to the postchemotherapy...
BACKGROUND:The identification of potential tumor markers can improve therapeutic planning and patient management. The objective of this study was to highlight the role of DNA methyltransferase 3b (DNMT3b) in esophageal squamous cell carcinoma (SCC).
METHODS:One hundred seventy‐three esophageal SCC samples were analyzed using immunohistochemical staining to correlate the expression of DNMT3b with...
INTRODUCTION:Intracranial hemangiopericytoma (HPC) is a malignant meningothelial tumor. Because of its rarity, few guidelines exist for optimal management.
METHODS:University of California at San Francisco patients managed for intracranial HPC were compiled into a single database based on a retrospective review of patient records. Univariate and multivariate regression was performed to determine...
BACKGROUND:The identification of potential tumor markers will help improve therapeutic planning and patient management. Therefore, the aim of this study was to highlight the role of DNA methyltransferase 1 (DNMT1) in bladder cancer.
METHODS:A total of 50 samples of nonmalignant urothelium, 65 of muscle‐invasive bladder cancers, 15 of distant metastasis, and 50 of nonmuscle‐invasive bladder cancers...
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