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Background and PurposeCholecystokinin (CCK) is secreted by intestinal I cells and regulates important metabolic functions. In pancreatic islets, CCK controls beta cell functions primarily through CCK1 receptors, but the signalling pathways downstream of these receptors in pancreatic beta cells are not well defined.
Experimental ApproachApoptosis in pancreatic beta cell apoptosis was evaluated using...
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