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We have studied the effects of rhTGF-β2, dexamethanosome (dex) and 1,25(OH)2D3on human bone marrow stromal (HBMS) cells in long-term culture. A fraction on HBMS expressed type I collagen (Col I) and osteopontin, and transient treatment (48 h) with dex increased the number of alkaline phosphatase (ALP) positive cells. Treatment with rhTGF-β2 inhibited DNA synthesis and attenuated the stimulatory effect...
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