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This study aims to evaluate the role of chymostatin in paraquat-induced acute lung injury. Institute of Cancer Research mice were randomly distributed into the NS, DMSO, chymostatin, paraquat or chymostatin treatment groups. Six mice from each group were intraperitoneally injected with chloral hydrate at 0, 1, 2, 4, 8, 12, 24 and 48 h after treatment administration. Blood samples were collected through...
Interleukin-17A (IL-17A) is involved in multiple inflammatory diseases. Our study was to investigate the role of IL-17A on acute lung injury (ALI) respectively induced by lipopolysaccharide (LPS) and paraquat (PQ) on mice. We built ALI mouse models respectively by single intraperitoneal (i.p.) injection with LPS or single gavage with PQ liquid. Two hours after the models were established, a dosage...
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