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Flavanones are the main compound of licorice, and the C'-4 position substitution is a significant structural feature for their biological activity. The ability of three selected flavanones (liquiritigenin, liquiritin, and liquiritin apioside) bearing different substituents (hydroxyl groups, glucose, and glucose–apiose sugar moiety) at the C'-4 position and a chalcone ( isoliquiritigenin, an isomer...
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