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The effects of pH (3–7), NaCl (0–6%), and temperature on pressure inactivation of hepatitis A virus (HAV) were determined. The HAV samples were treated at 400 MPa for 1 min at 5, 20, and 50 °C. Decreasing solution pH enhanced pressure inactivation of HAV. This enhanced inactivation effect was most evident at 20 °C. A baroprotective effect was observed for NaCl concentrations from 1 to 6%. For example,...
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