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The glutamatergic projection from the ventral subiculum of the hippocampus (vSUB) to the nucleus accumbens (NAc) shell has been reported to play a key role in drug‐related behavior. The GluN2B subunit of N‐methyl‐D‐aspartate receptors (NMDARs) in the NAc can be selectively elevated after the retrieval of drug‐conditioned memory. However, whether the increased GluN2B‐containing NMDARs (GluN2B‐NMDARs)...
Our previous studies have demonstrated that morphine-induced conditioned place preference (CPP) can be inhibited by 2 Hz electroacupuncture (EA). This inhibition can be blocked by either the opioid receptor antagonist naloxone (i.p.) or lesion in the nucleus accumbens (NAc), providing evidence that endogenous opioid system in the NAc mediates the effects of EA. Here we report that 1) A single session...
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