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ABSTRACTMore than 80% of the patients affected by hereditary hemochromatosis, a common inherited iron disorder, are homozygotes for the 845G → A (C282Y) mutation of the HFE gene. However, depending on the population, 10–20% of hereditary hemochromatosis can be linked either to other HFE genotypes, particularly the compound heterozygous state for C282Y and the 187 C → G (H63D) mutation, or to mutations...
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