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AimmiR‐145 is a candidate tumor suppressor miRNA. However, it is unknown whether miR‐145 is involved in the invasion of hepatocellular carcinoma (HCC). Therefore, we aimed to explore the effect and mechanism of miR‐145 in the control of HCC cell invasion.
MethodsHCC cell invasion was evaluated by transwell assays after transfection with pre‐miR‐145 or anti‐miR‐145. A luciferase reporter assay was...
Aim: 5‐Fluorouracil (5‐FU) is one of the most commonly used chemotherapeutic drugs. Resistance to 5‐FU is a major cause of chemotherapy failure in advanced‐stage hepatocellular carcinoma (HCC). Green tea polyphenol Epigallocatechin‐3‐gallate (EGCG) plays a critical role in growth inhibition and apoptotic induction in HCC cell lines. The aim of this study is to investigate whether EGCG can enhance...
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