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A substantial understanding of nanoparticles recognition and uptake by biological cells and tissues is very important for reaching their fullest potential in biomedical research. In this work, we investigated the cell endocytosis of iron oxide nanoparticles by both normal breast epithelial cells (MCF10A) and cancer breast epithelial cells (MCF7) using a combination of atomic force microscope (AFM)...
This paper presents simulation study of the action potential waveforms of different ventricular cell types based on experimental studies of transmural electrophysiological heterogeneities in control and failing human hearts. The results show that prolonged action potential duration (APD) and APD rate-adaptation are markedly transmural heterogeneous in heart failure than those in controlled heart which...
The goal of our research is try to explain the electrophysiological mechanisms of alternation in T-wave of ECG in ultrahigh static magnetic field (SMF). The magneto-hydrodynamics model study shows that ultrahigh SMF can induce reduction in the volume flow rate of the blood in human aorta more than 10%, thus may lead to anoxia condition of acute ischemia. Using an ionic-based theoretical model of the...
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