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1-Nitropyrene (1-NP) is a mutagenic and carcinogenic pollutant very widespread in the environment. However, the relative investigations on genotoxicity, oxidative stress and metabolic enzymes in lungs of mammalian caused by 1-NP have not been fully established. In this study, the 1-NP solutions at 3 dosages (1.0×10−5, 4.0×10−5 and 1.6×10−4mg/kg body weight) were respectively given to rats by the intratracheal...
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