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Objective
We aimed to assess the ability of semiautomated electric source imaging (ESI) from long‐term video‐electroencephalographic (EEG) monitoring (LTM) to determine the epileptogenicity of temporopolar encephaloceles (TEs) in patients with temporal lobe epilepsy.
Methods
We conducted a retrospective study involving 32 temporal lobe epilepsy patients with TEs as potentially epileptogenic lesions...
Objective
To determine the diagnostic yield of in‐hospital video–electroencephalography (EEG) monitoring to document seizures in patients with epilepsy.
Methods
Retrospective analysis of electronic seizure documentation at the University Hospital Freiburg (UKF) and at King's College London (KCL). Statistical assessment of the role of the duration of monitoring, and subanalyses on presurgical patient...
Objectives
High counts of averaged interictal epileptiform discharges (IEDs) are key components of accurate interictal electric source imaging (ESI) in patients with focal epilepsy. Automated detections may be time‐efficient, but they need to identify the correct IED types. Thus we compared semiautomated and automated detection of IED types in long‐term video‐EEG (electroencephalography) monitoring...
Because oral pharmacological treatment of neocortical focal epilepsy is limited due to common systemic side effects and relatively low drug concentrations reached at the epileptic foci locally, application of antiepileptic agents directly onto the neocortical focus may enhance treatment tolerability and efficacy. We describe the effects of cortically applied sodium valproate (VPA) in two patients...
ObjectiveInformation on the relative timing of electroencephalography (EEG) seizure onset, ictal tachycardia (ITC), and first other clinical seizure manifestations is crucial for an understanding of the potential benefit of ITC‐detection based closed‐loop intervention systems for epilepsy treatment. This study analyzes the temporal relation of ITC, other clinical signs, and seizure onset in relation...
ObjectiveFocal cortical dysplasia (FCD) is currently recognized as the most common cause of neocortical pharmacoresistant epilepsy. Epilepsy surgery has become an increasingly successful treatment option. Herein, the largest patient cohort reported to date is analyzed regarding long‐term outcome and factors relevant for long‐term seizure control.
MethodsTwo hundred eleven children and adults undergoing...
PurposeThe new International League Against Epilepsy (ILAE) classification for focal cortical dysplasia (FCD) differentiates between patients with isolated FCD (type 1) and FCD with an associated hippocampal sclerosis (HS) (type 3a). In contrast to the former FCD classification by Palmini, which considered only histologic features, the novel ILAE classification also relies on magnetic resonance imaging...
Purpose: To assess the efficacy and tolerability of chronic high‐frequency deep brain stimulation (DBS) in adult patients with progressive myoclonic epilepsy (PME) syndromes.
Methods: Five adult patients (four male, 28–39 years) with PME underwent chronic high‐frequency DBS according to a study protocol that had been approved by the local ethics committee. Electrodes were implanted in the substantia...
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